The TUNEL observation of murine follicular oocyte cleaving with repeated superovulation

Follicle and Oocyte Relationships During Superovulation in the Heifer

Effect of nutrition and superovulation on oocyte morphology, follicular fluid composition and systemic hormone concentrations in ewes.

The objective was to determine the effect of dietary intake on follicle and oocyte morphology in unstimulated and superovulated ewes. Fifty-four ewes were fed grass meal at 0.5, 1.0 or 2.0 times maintenance energy requirements (M) for 32 days. Oestrous cycles were synchronized using progestagen pessaries and either unstimulated or superovulated with 200 mg pig FSH. The ewes were killed and ovar...

Metformin therapy in a hyperandrogenic anovulatory mutant murine model with polycystic ovarian syndrome characteristics improves oocyte maturity during superovulation

BACKGROUND Metformin, an oral biguanide traditionally used for the treatment of type 2 diabetes, is widely used for the management of polycystic ovary syndrome (PCOS)-related anovulation. Because of the significant prevalence of insulin resistance and glucose intolerance in PCOS patients, and their putative role in ovulatory dysfunction, the use of metformin was touted as a means to improve ovu...

Repeated superovulation and surgical recovery of embryos in the ewe.

Repeated superovulation using three treatments of pFSH at intervals of 45 to 55 days during the same breeding season was carried out in 18 Préalpes ewes. The embryos were recovered by surgery after the first two treatments and by slaughter after the last one at Day 6. Three lots of control ewes (n = 5 or 6) receiving the same superovulation treatment were slaughtered respectively at the same ti...

The Correlation of the Follicular Fluid Levels of Anti-Mullerian Hormone and Beta Human Chorionic Gonadotropin with Oocyte Matura-tion

Background: Follicular fluid (FF) plays a key role in preparing a microenvironment for the development and fertilization of oocytes. Moreover, biochemical and hormonal changes in the FF surrounding the oocyte can affect its quality and successful fertilization. The present study was conducted to investigate the relationship of beta human chorionic gonadotropin (beta-HCG) and anti-mullerian horm...